Before BC
1. Henry R. Kilgore*,†, Itamar Chinn.*, Peter Mikhael.*, Ilan Mitnikov*, et al., Protein codes promote selective subcellular compartmentalization. Science. 387, 1095-1011 (2025).
Spotlight: Songtao Ye, Choon Leng So and Danfeng Cai. Cracking the protein compartmentalization code with ProtGPS. Trends in Biochem. Sci. 2025.
Research Highlight: Jonathon A. Ditlev. and Julie Foreman-Kay. Beyond peptide targeting sequences: machine learning of cellular condensate localization. Cell Research. 2025.
Elie Dolgin AI Reveals Hidden Interior Design Rules of the Cell, IEEE Spectrum.
Elie Dolgin, How phase separation is revolutionizing biology, Nature, 2024.
BioByte 074, Decoding Biology
2. Henry R. Kilgore*,†, Kalon Overholt*, and Peter Mikhael.*, et al. Distinct chemical environments in biomolecular condensates. Nature Chemical Biology 20, 291-301 (2024).
Bakhtyar Sepheri, Kevin Drew and José A. Villegas. Come for the atmosphere, stay for the interactions: Deciphering small molecule partitioning into biomolecular condensates. Cell Chemical Biology, Nov. 2023.
3. Henry R. Kilgore* and Richard A. Young*. Learning the chemical grammar of biomolecular condensates. Nature Chemical biology 18, 1298-1306 (2022).
4. Henry R. Kilgore†, Chase R. Olson†, Mohammad Movassaghi, and Ronald T. Raines. n* Interactions Modulate the Disulfide Reduction Potential of Epidithiodiketopiperazines. Journal of the American Chemical Society. 142, 15107-15115 (2020)
5. Yun Hu†, Jessica M. Roberts†, Henry R. Kilgore†, Amirah Mat Lani, Ronald T. Raines, Jennifer M. Schomaker. Triple, Mutually Orthogonal Cycloadditions Through the Design of Electronically Activated SNO-OCTs. Journal of the American Chemical Society 142, 18826-18835 (2020).
6. Henry R. Kilgore†, Andrew P. Latham†, Valerie T. Ressler, Bin Zhang, and Ronald T. Raines. Structural and Dynamic Features of Glycosylated Human Ribonuclease 1. Biochemistry 59, 3148-3156 (2020).
7. Henry R. Kilgore and Ronald T. Raines. Disulfide Chromophores Arise from Stereoelectronic Effects. Journal of Physical Chemistry B 124, 3931-3935 (2020).
8. Henry R. Kilgore and Ronald T. Raines. n* Interactions Modulate the Properties of Cysteine Residues and Disulfide Bonds in Proteins. Journal of the American Chemical Society 140, 17606–17611 (2018).
Contributing author papers
9. Aniekan, Okon. Anton Morgunov, Jinyi Yang, Yana D. Petri, Henry R. Kilgore, Yanfeng Li, Eric. R. Streiter, Ronald T. Raines. Hydrophilic α-Aryl-α-Diazoamides for Protein Esterification, Synlett. In press.
10. Cong Wang, Henry R. Kilgore, Andrew P. Latham, Bin Zhang. Nonspecific yet selective interactions contribute to small molecule condensate binding. Journal of Chemical Theory and Computation 20, 10247-10258 (2024).
11. Alessandra Dall’Agnese†, Jesse M. Platt†, … Henry R. Kilgore, et al. The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance. Nature Communications 13, 7522 (2022).
12. Wen Chyan†, Henry R. Kilgore†, and Ronald T. Raines. Cytosolic Uptake of Large Monofunctionalized Dextrans. Bioconjugate Chemistry 29, 19420-19429 (2018).
13. Wen Chyan, Henry Kilgore, Brian Gold, and Ronald T. Raines. Electronic and Steric Optimization of Fluorogenic Probes for Biomolecular Imaging. Journal of Organic Chemistry 82, 4297-4304 (2017).
*Corresponding author
†Contributed equally to this work.